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ASUS Pro WS X299 Sage II LGA 2066 CEB Motherboard


  • Intel X299
  • Intel Socket 2066 Core X-Series Processors
  • Supports Intel Virtual RAID on CPU (VROC)
  • * Refer to www.asus.com for CPU support list
  • Intel Core X-series Processors (6-core above)
  • DDR4 4266(O.C.)/ 4200(O.C.)/ 4133(O.C.)/ 4000(O.C.)/ 3600(O.C.)/ 2933/ 2666/ 2400 MHz Non-ECC, Un-buffered Memory
  • Supports Intel Extreme Memory Profile (XMP)
  • * Hyper DIMM support is subject to the physical characteristics of individual CPUs.
  • * Actual memory frequency differs from Intel CPU types and memory module. Please check Intel official site for more detail about the memory types supported by each CPU.

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ASUS PRO WS X299 SAGE II LGA 2066 Intel X299 SATA 6Gb/s CEB Intel Motherboard


ASUS Pro Workstation motherboards are designed for professionals in AI training, deep learning, animation, 3D rendering or media production. Featuring expandable graphics, extensive storage, impressive connectivity and exceptional overall performance and reliability, Pro Workstation motherboards are the ideal solution for creative professionals. Each motherboard includes centralized management software with support for out-of-band management, so they’re also an efficient and cost-effective option for IT administrators.

Breakthrough Performance

Tune in your way

Cool to the core

Audio & Personality


Dual Intel®
2.5G LAN

2 x USB 3.2 Gen2
(1x Type-A &
1x Type-C)

8CH Audio with
DTS support

PCI-E Gen3 x16
(x16 Link)

PCI-E Gen3 x16
(x8/0 link)

PCI-E Gen3 x16
(x16/x8 link)

PCI-E Gen3 x16
(x8/0 link)

PCI-E Gen3 x16
(x16/x8 link)

PCI-E Gen3 x16
(x8/0 link)

Crystal Sound3

PCI-E Gen3 x16
(x16/x8 link)

DIGI + Power Control

LGA 2066 Sockets for Intel® Core™ X-series processors

3 x U.2 ports

8 x DDR4 4266 MHz (O.C.) support

1 x vertical M.2, up to 22110

ASUS SafeSlot

ThunderboltEX 3 card header

8 x SATA3 6Gb/s ports

1 x M.2, up to 2280

Breakthrough Performance

Intel®’s high-end desktop platform raises the stakes with updated Intel Core™ X-Series Processors that boast cores, cache, and bandwidth. The Pro WS X299 Sage II is ready for the additional processing power that plows through CPU-intensive tasks, and the extra bandwidth allows you to add more GPUs and NVMe SSDs to accelerate a wide range of work.

  • Multi-GPU support
  • Memory
  • Connectivity
  • Storage

Four Dual-slot GPUs support

Pro WS X299 Sage II fits up to four dual-slot graphics cards and supports both NVIDIA® SLI™ and AMD CrossFire™ 4-way configurations to enable multi-GPU setups that harness the full power of the latest graphics technologies, including NVIDIA® Quadro®. NVIDIA® Quadro® is the perfect complement to Pro WS X299 Sage II, delivering the best performance for design, modeling, medical research, and processing-intensive simulation and rendering applications.

Back to Breakthrough Performance

Tune it your way

Comprehensive controls form the foundation of the ASUS X299 motherboards. The Pro WS X299 Sage II packs flexible tools to tune every aspect of your system to deliver the performance that you desire.

Overclock CPU
Auto Tuning
CPU : Intel LGA 1151 i9-10980XE | Motherboard : Pro WS X299 Sage II
DRAM : CORSAIR CMK32GX4M4E4133C19R Ver. 4.31 |
Power : Delta DPS-1200QB | Water-cooling : Bitspower SC6 PWM | OS: Windows 10
  • AI overclocking
  • 5-Way Optimization

AI Overclocking

ASUS AI Overclocking makes automatic tuning faster and smarter than ever before. Available in Windows or directly through the UEFI, it profiles the CPU and cooling to predict the optimal configuration for each individual system.

CPU Potential

A proprietary algorithm evaluates the capabilities of your CPU

Cooling Capability

Onboard intelligence watches system vitals such as temperature, fan speed, and power draw to gauge cooling performance

5-Way Optimization

One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.
An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
Fans stay quiet as a whisper for everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.
All-new stress test that allows users to optimize and overclock for CPU or memory-centric workloads.

Back to Tune it your way

Cool to the core

Effective cooling is extremely important, even at stock speeds. That is why the Pro WS X299 Sage II allows consolidated cooling control of the entire system, even for the most hardcore rigs. It comes equipped with onboard heatsinks, an array of fan headers, the Fan Extension Card II, options for water pump and AIO headers.

  • Heatsinks
  • Cooler by design

Multiple Ultra-efficient heatsinks

Pro WS X299 Sage II features a thoughtful thermal design to ensure maximum performance with no CPU throttling. Its ultra-efficient VRM heatsink with a metal fin array maximizes surface area for heat dissipation, and its heatsinks and a connecting heat-pipe that’s situated in the direct path of airflow combine to ensure optimal cooling performance — even under the most demanding workloads.

M.2 heatsink

Pro WS X299 Sage II features an ultra-efficient heatsink to reduce M.2 SSD temperatures for optimal storage performance and improved SSD longevity.

Back to Cool to the core



Weight 2 kg
Dimensions 30 × 30 × 15 cm


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